The input data useful for the design of a silencer are mainly the type of fluid (and its degree of physicochemical aggressiveness with respect to the envisaged silencer), its thermodynamic state (flow rate, pressure, temperature, density), the level of acoustic performance required (insertion loss, remaining sound power), the level of aerodynamic performance required (total pressure loss often called pressure drop), and the space available (dimensions of the upstream network, space available for the silencer, downstream interfacing if applicable). In very numerous cases, the reaction to fire of considered materials  is also taken into account.

In the case of realization in the food industry, in pharmaceuticals, or in hospitals, specific constraints related to hygiene are involved and may necessitate the use of particular absorbing fillings (with waterproof washable linings) or the use of stainless steels.

Other parameters may be involved such as the authorized mass, the longevity required or the available budget.